OpenAI's GPT-5 Pro solves physics in minutes
PLUS: Claude gains new 'Skills', Microsoft's AI learns your PC, and the great AI bubble debate
Welcome back, AI’ers!
Here’s What’s On The Menu For Today
OpenAI's GPT-5-Pro tackles complex science
Anthropic gives Claude customizable 'Skills'
Microsoft's Copilot learns to control your PC
AI ON MY MIND
Happy Friday,
OpenAI is signaling a major push into scientific discovery, highlighted by a stunning demonstration from its upcoming GPT-5-Pro model. The AI tackled a complex physics problem in under 30 minutes, a feat that took a human expert days to solve.
With the company now hiring top physicists and positioning its models as the 'next great scientific instrument', the era of AI-powered research seems to be arriving fast. What could this mean for the future pace of breakthroughs in humanity's most challenging fields?
By the way, I've been getting questions about how AI works in practice, so I'm launching a separate newsletter that dives deeper into real business applications and practical advice. [Click here if you're interested].
-Jelani Fuel (Co-founder of Best of AI)
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TODAY’S TOP STORIES

AI's Science Breakthrough
The Recap: OpenAI is making a serious push into scientific discovery, hiring theoretical physicist Alex Lupsasca for its new science division. The move came after its upcoming GPT-5-Pro model solved a complex physics problem in under 30 minutes—a task that took the expert days to complete.
Unpacked:
The initiative aims to combine AI models with scientific tooling, positioning itself as 'the next great scientific instrument' for researchers.
Lupsasca said GPT-5-Pro 'completely changed his mind' on AI's role in research after it solved the challenging problem for him in less than half an hour.
OpenAI VP Kevin Weil also revealed that GPT-5 has already shown 'limited novel research abilities' across diverse fields like math, quantum theory, and biology.
Bottom line: This move signals OpenAI is pursuing a multi-front strategy, aiming to power fundamental scientific breakthroughs alongside its consumer-facing applications. AI is quickly becoming a powerful partner for researchers, accelerating the pace of discovery in humanity's most complex fields.

Anthropic Gives Claude New 'Skills'
The Recap: Anthropic just launched Skills for Claude, a new feature that lets organizations package custom workflows, code, and proprietary data into folders that the AI can use autonomously to handle specific tasks.
Unpacked:
Skills operate as a folder-based system containing instruction files, scripts, and reference materials that Claude loads dynamically based on the task's relevance.
An interactive "skill-creator" assistant lets users build custom skills with no coding expertise required, making the process accessible to non-technical teams.
Multiple skills can also coordinate on complex tasks, combining things like brand guidelines with financial reporting templates in a single workflow.
Bottom line: By packaging expertise into simple folders instead of code, Anthropic lowers the barrier for companies to deploy custom AI agents. This approach makes it more practical for businesses to infuse their unique internal knowledge into AI for scalable automation.
MY FAVORITE AI TOOLS

Relevance is my favorite AI tool right now (even more so than N8N).
Here’s why:
It’s an AI agent building tool that doesn’t require you to build out the logic using nodes. Instead, you use natural language to build out these agents. But the best thing imo is that you can build AI Agent teams.
Like agents talking to each other completing a goal until its done. It’s nuts. No other tool on the market is doing this. You have to check it out.
(Try it out →Link)
👾 AI Tools We Use Everyday
➡️ N8N for AI Agents - Literally use this everyday to write this newsletter (link)
➡️ Axiom AI - AI Browser automation to scrape anything on the web (link)
➡️ GummySearch - AI Reddit research (link)
Tools are sourced from our database and are not sponsored or affiliated.
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MORE NEWS

Microsoft's AI Learns Your PC
The Recap: Microsoft is starting to test "Copilot Actions" in Windows 11, a new feature that allows its AI assistant to directly control your PC to automate multi-step tasks on your local files. The preview is rolling out first to members of the Windows Insider Program.
Unpacked:
This update turns Copilot into a true computer-use agent, capable of mimicking clicks and typing to complete workflows like resizing a batch of photos.
To address security concerns, the feature is disabled by default, runs in a contained environment, and allows you to watch and take over at any moment.
This is a strategic move to drive Windows 11 upgrades and compete in the emerging AI PC market, which Microsoft estimates will see over 50 million units sold in the next year.
Bottom line: Copilot is evolving from a chatbot into an active partner that can execute tasks directly on your machine. Microsoft is betting this hands-on capability will make Windows an essential platform in the age of AI-powered computing.
OTHER NEWS YOU MAY LIKE
Experts warn that the massive influx of capital into the AI sector is showing symptoms of a bubble, with leaders from Amazon, Goldman Sachs, and even OpenAI's Sam Altman acknowledging the overexcitement.
Bethesda revealed that its long-running 'Radiant AI' system for NPCs in games like Skyrim and Starfield becomes less noticeable as it gets more advanced, with improvements making character behaviors more natural and seamlessly integrated.
Researchers highlighted the rising threat of AI-generated explicit deepfakes following a case in Sydney, noting that 95-99% of targets are women and that this represents a continuation of gendered violence using new technology.
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AI ON SOCIAL
Just give me 30 seconds to change and capture this moment!
Because we’ve got a new playground to get creative and build workflows using all AI models and mediums in one connected space, Fuser Studio.
If you don’t know where to start, they’ve got great templates for video
— Gizem Akdag (@gizakdag)
7:03 PM • Oct 16, 2025
Claude + skills (canvas-design) made me this lovely coffee table book... think I'm gonna have to cmd+p this 🤓
— Alexander Bricken (@ambricken)
9:55 PM • Oct 16, 2025
AI ART
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THAT’S IT FOR TODAY
Until next time, stay safe.
-Best of AI Team
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