OpenAI partners with Hollywood over Sora deepfakes

PLUS: 'ChatGPT for Doctors' hits $6B, Claude gets an upgrade, and Napster's AI pivot

Author

Jelani Abdus-Salaam
October 21, 2025

In partnership with

Welcome back, AI’ers!

Here’s What’s On The Menu For Today

  • OpenAI's partnership with Hollywood over Sora

  • 'ChatGPT for Doctors' hits $6B valuation

  • Anthropic's Claude gets a professional upgrade

  • Napster pivots to AI with holographic companions

AI ON MY MIND

Happy Tuesday,

Unauthorized deepfakes on OpenAI's Sora 2 platform have pushed the company to partner with actor Bryan Cranston and major Hollywood groups. The collaboration is a direct response to the misuse of likenesses and aims to implement stronger safety measures for generative video.

This incident has accelerated a crucial industry conversation, moving from reactive takedowns to proactive policies. But will this landmark agreement set a true industry-wide precedent for how consent and creator rights are handled in the age of AI?

By the way, I've been getting questions about how AI works in practice, so I'm launching a separate newsletter that dives deeper into real business applications and practical advice. [Click here if you're interested].

-Jelani Fuel (Co-founder of Best of AI)

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TODAY’S TOP STORIES

Sora's Hollywood Handshake

The Recap: OpenAI is partnering with actor Bryan Cranston, SAG-AFTRA, and major Hollywood agencies after unauthorized deepfakes of the actor appeared on its Sora 2 platform. The group released a joint statement vowing to implement stronger guardrails to protect performers' likenesses.

Unpacked:

  • The collaboration was sparked by unauthorized deepfakes of Bryan Cranston circulating on Sora 2, including one that showed him taking a selfie with a synthetic Michael Jackson.

  • This incident brought a simmering conflict to a boil over OpenAI's initial "opt-out" policy, with this agreement solidifying a crucial shift toward a required "opt-in" protocol for using an artist's voice and likeness.

  • The move rallies support for federal legislation like the NO FAKES Act, a bill aimed at protecting individuals from unauthorized AI replicas that both OpenAI and the creative unions endorse.

Bottom line: This partnership marks a critical step in establishing ethical standards for generative video, moving beyond reactive fixes to proactive industry collaboration. It signals that the future of AI content creation will be defined just as much by consent and creator rights as by technological power.

'ChatGPT for Doctors' Hits $6B Valuation

The Recap: Medical AI startup OpenEvidence has raised $200M, doubling its valuation to a massive $6 billion in just three months. The platform gives clinicians instant access to verified medical knowledge, driving its rapid adoption.

Unpacked:

  • The platform's credibility comes from being trained exclusively on trusted medical sources, including prestigious publications like JAMA and The New England Journal of Medicine.

  • Its user base is soaring, with doctors and nurses conducting 15 million monthly consultations on the platform since July to get faster, more reliable answers.

  • The latest $200M funding round showcases incredible investor confidence, doubling the company's valuation to $6 billion in just three months.

Bottom line: OpenEvidence's rapid ascent highlights the immense demand for specialized AI tools that can safely handle high-stakes information. This model of using curated, expert-vetted data could become the standard for professional AI applications everywhere.

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Here’s why:

It’s an AI agent building tool that doesn’t require you to build out the logic using nodes. Instead, you use natural language to build out these agents. But the best thing imo is that you can build AI Agent teams.

Like agents talking to each other completing a goal until its done. It’s nuts. No other tool on the market is doing this. You have to check it out.

(Try it out →Link)

👾 AI Tools We Use Everyday

➡️ N8N for AI Agents - Literally use this everyday to write this newsletter (link)

➡️ Axiom AI - AI Browser automation to scrape anything on the web (link)

➡️ GummySearch - AI Reddit research (link)

Tools are sourced from our database and are not sponsored or affiliated.

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MORE NEWS

Anthropic's Claude Gets an Upgrade

The Recap: Anthropic launched a major update for its coding assistant by bringing it to the browser, and also introduced 'Claude for Life Sciences' to help researchers analyze complex data.

Unpacked:

  • Claude Code now runs directly in a browser, giving developers a streamlined experience for connecting GitHub repos, managing multiple tasks, and getting automatic pull requests without using a command line.

  • The new '[Claude for Life Sciences](https://www.anthropic.com/news/claude-for-life-sciences)' platform connects to research portals like PubMed to help accelerate research by assisting with literature reviews and data analysis.

  • These releases show Anthropic is moving toward a strategy of building specialized professional tools that cater to specific industries alongside making its core products more accessible.

Bottom line: Anthropic is pushing beyond general-purpose chatbots to create targeted, industry-specific assistants. This shift provides professionals with powerful AI that integrates directly into their existing workflows.

Napster's AI Pivot: Holograms for Your Desk

The Recap: The iconic music brand Napster is pivoting to AI, launching a new platform called Napster 26 that features holographic AI companions projected from a special display for your Mac.

Unpacked:

  • The system uses a $99 holographic display called Napster View that projects 3D AI assistants above Mac screens, requiring no special glasses for the effect.

  • Beyond a library of over 15,000 companions, users can create AI digital twins of themselves to handle tasks like attending meetings or managing their online presence.

  • This shift follows Napster's acquisition by 3D technology firm Infinite Reality for $207M, with subscriptions starting at $19 per month for the new AI service.

Bottom line: Napster's move is a wild bet on a new kind of human-computer interface, moving AI companions from text boxes to physical space on our desks. This experiment will test if users are ready for a more literal and visible AI presence in their daily workflow.

OTHER NEWS YOU MAY LIKE

DeepSeek released its new OCR model, a vision language AI designed to extract and understand text from within images.

Science Corp. restored vision in some blind patients using its PRIMA system, a brain-computer interface that combines a retinal implant with specialized eyewear.

Reid Hoffman clashed with David Sacks over the future of AI development, continuing a public debate among Silicon Valley leaders sparked by Anthropic co-founder Jack Clark's recent essay.R US

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THAT’S IT FOR TODAY

Until next time, stay safe.

-Best of AI Team

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