Grok 3.5
Plus AI finds an Alzheimer's cure?
Welcome back, AI’ers!
Today's post is 427 words, a ~3-minute read.
Here’s What’s On The Menu For Today
🧠 AI On My Mind
🤖 Grok 3.5
✨ A Cure For Alzheimer's
📰 News Hot Off The Press
AI ON MY MIND
Happy Wednesday!
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TODAY’S TOP STORIES

AI uncovers a key trigger behind Alzheimer's
AI just pinpointed PHGDH—a gene that disrupts brain regulation and may be a root cause of Alzheimer’s. This flips it from a warning sign into a treatment target.
Why it matters:
This shifts the conversation. We’re not just spotting the disease earlier—we may be able to stop it before it starts.
The update:
Researchers used AI to identify PHGDH’s impact.
The gene affects brain metabolism in a way that contributes to Alzheimer’s
One compound already on the shelf might help treat it
Who's behind it:
UC San Diego ran the study
Dr. Robert Tauffer said this is the first time PHGDH’s role has been shown like this
What’s next:
Still early. Clinical use will take time.
What to watch:
This shows how AI isn’t just about speed or automation—it’s starting to play a real role in discovering life-saving treatments.
The takeaway:
If this holds up, PHGDH gives us a new way to fight a disease that hits millions. That’s a serious unlock.

Elon Musk drops Grok 3.5
Elon just announced the beta of Grok 3.5. It’s built to handle complex technical questions—no internet required.
Why it matters:
This version’s designed to go deep. Rocket science. Chemistry. The stuff search engines usually fail at.
The rollout:
Beta access goes to “SuperGrok” users
The model gives answers without relying on web scraping
What makes it different:
Focuses on generating original insight
Built to cut through fluff and give technical users what they need
Caveat:
It’s invite-only (for now)
Why it’s worth tracking:
If Grok 3.5 delivers, it’ll push AI from generalist to specialist. That’s where things get useful fast.
Bottom line:
Grok 3.5 is a glimpse of where high-performance AI is headed—and who it’s being built for.
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👾 Other AI Tools We Use Everyday
➡️ N8N for AI Agents - Literally use this everyday to write this newsletter (link)
➡️ Axiom AI - AI Browser automation to scrape anything on the web (link)
➡️ GummySearch - AI Reddit research (link)
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AI On Social
✨ Runway Releases Gen-4 References
Today we are releasing Gen-4 References to all paid plans. Now anyone can generate consistent characters, locations and more. With References, you can use photos, generated images, 3D models or selfies to place yourself or others into any scene you can imagine.
More examples
— Runway (@runwayml)
5:14 PM • Apr 30, 2025
✨Introduction To Vibe Marketing
INTRODUCTION TO "VIBE MARKETING" (23 minute tutorial/demo explained simply)
— GREG ISENBERG (@gregisenberg)
5:46 PM • Apr 30, 2025
What you will discover when you join me live:
✅ Why you can have zero coding skills and still sell this to businesses for thousands of dollars
✅ My "A.P.P. framework" I use to build valuable in-demand apps using AI
🔴 Live Demo of me building a micro app together with you in real time
✅ Finding hungry buyers willing to pay $2,000-$10,000 for simple, problem solving tools
AI ART
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THAT’S IT FOR TODAY
Until next time, stay safe.
-Best of AI Team
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