Google's Gemma AI uncovers new cancer therapy
PLUS: Proof the AI gold rush is real and Anthropic's cheaper Claude
Welcome back, AI’ers!
Here’s What’s On The Menu For Today
Google AI generates a new cancer therapy
TSMC earnings confirm the AI gold rush
Cloudflare challenges Google on AI content
The push for new AI web content norms
AI ON MY MIND
Happy Thursday,
Researchers from Google and Yale have demonstrated a major step forward for AI in medicine. An AI model was used to generate a novel hypothesis for cancer therapy, which was then successfully validated in a lab.
This represents a significant move from AI simply analyzing existing data to becoming a creative partner in scientific discovery. The key question is: how quickly could this new collaborative approach between AI and human researchers accelerate breakthroughs in other complex fields?
By the way, I've been getting questions about how AI works in practice, so I'm launching a separate newsletter that dives deeper into real business applications and practical advice. [Click here if you're interested].
-Jelani Fuel (Co-founder of Best of AI)
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TODAY’S TOP STORIES

AI's Cancer Breakthrough
The Recap: Google and Yale researchers used an AI model to generate a completely new hypothesis for a cancer therapy pathway. In a major milestone for AI in science, scientists then experimentally validated the prediction in living cells.
Unpacked:
The model was tasked with finding a way to make "cold" tumors, which are notorious for evading the immune system, visible to the body's defenses.
It identified that the drug silmitasertib, when paired with low-dose interferon, could effectively "heat up" these tumors.
Experimental validation confirmed the AI's hypothesis, showing a 50% increase in the signals that help immune cells recognize and attack cancer.
Bottom line: This marks a significant shift from AI just analyzing data to actively generating novel scientific ideas. This new partnership between AI and lab research could dramatically speed up the pace of discovery in medicine and beyond.

The AI Gold Rush Is Real
The Recap: TSMC, the world's largest chipmaker, just posted a record-breaking 39% jump in quarterly profit, smashing estimates. The surge is fueled almost entirely by the insatiable global demand for advanced AI chips.
Unpacked:
The company’s High-Performance Computing division, which includes AI, now accounts for a staggering 57% of revenues.
Demand is concentrated on the most advanced technology, with cutting-edge chips (7-nanometer and smaller) making up 74% of total wafer sales.
Confidence in the AI boom is so high that TSMC raised its revenue forecast for 2025 to the mid-30% range, signaling sustained long-term growth.
Bottom line: TSMC's blockbuster earnings provide concrete financial proof of the massive investment pouring into AI infrastructure. It also highlights the critical dependency the entire AI ecosystem has on a handful of highly specialized chip manufacturers.
MY FAVORITE AI TOOLS

Relevance is my favorite AI tool right now (even more so than N8N).
Here’s why:
It’s an AI agent building tool that doesn’t require you to build out the logic using nodes. Instead, you use natural language to build out these agents. But the best thing imo is that you can build AI Agent teams.
Like agents talking to each other completing a goal until its done. It’s nuts. No other tool on the market is doing this. You have to check it out.
(Try it out →Link)
👾 AI Tools We Use Everyday
➡️ N8N for AI Agents - Literally use this everyday to write this newsletter (link)
➡️ Axiom AI - AI Browser automation to scrape anything on the web (link)
➡️ GummySearch - AI Reddit research (link)
Tools are sourced from our database and are not sponsored or affiliated.
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MORE NEWS

Cloudflare Draws a Line in the Sand
The Recap: Web infrastructure giant Cloudflare is automatically updating millions of websites to give them explicit control over how AI models use their content. This new "Content Signals Policy" directly challenges Google's practice of scraping the web to power its AI Overviews.
Unpacked:
Publishers are backing the change after seeing referral traffic plummet, with one study showing clicks were nearly cut in half on pages with Google's AI summaries.
The policy adds new rules to the
robots.txt
file, allowing site owners to separately approve content use for traditional search, AI training, and real-time AI answers.This move is framed as a license agreement to create legal risk for Google, leveraging Cloudflare's position backing nearly 20% of the web to force a change.
Bottom line: This represents a significant push to establish new norms for how AI interacts with web content. It’s a high-stakes effort to ensure the web's original creators aren't left behind as AI answer engines become more common.
OTHER NEWS YOU MAY LIKE
Mint Mobile featured a real actress named Tilly Norwood in a new ad with Ryan Reynolds, poking fun at the recent controversy surrounding a viral AI-generated actress with the same name.
Hollywood pushed back against the rise of AI-generated performers like Tilly Norwood, with actors questioning the ethics and impact of replacing human talent in the entertainment industry.
Maximum Effort leveraged the viral debate over AI actors for a new Mint Mobile campaign, illustrating a trend of brands engaging with timely tech controversies for marketing.
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AI ON SOCIAL
2 Sora 2 updates:
- Storyboards are now available on web to Pro users
- All users can now generate videos up to 15 seconds on app and web, Pro users up to 25 seconds on web— OpenAI (@OpenAI)
3:18 AM • Oct 16, 2025
Claude can now use Skills.
Skills are packaged instructions that teach Claude your way of working.
— Claude (@claudeai)
4:07 PM • Oct 16, 2025
Introducing Veo 3.1 and Veo 3.1 Fast, our latest state of the art video models with:
- richer native audio
- better cinematic styles
- reference to video
- transitions between frames
- video extensions— Logan Kilpatrick (@OfficialLoganK)
4:06 PM • Oct 15, 2025
AI ART
Can You Spot The AI-Generated Image?Click "Picture One", "Picture Two", "Both", "None" |
RANDOM PROMPT OF THE DAY
Copy and paste this prompt 👇
"I want you to act as an biblical translator. I will speak to you in english and you will translate it and answer in the corrected and improved version of my text, in a biblical dialect. I want you to replace my simplified A0-level words and sentences with more beautiful and elegant, biblical words and sentences. Keep the meaning same. I want you to only reply the correction, the improvements and nothing else, do not write explanations. My first sentence is [PROMPT].[TARGETLANGUAGE]."
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THAT’S IT FOR TODAY
Until next time, stay safe.
-Best of AI Team
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